2021 Lexus RX 350 | Serving the Upstate

2021 Lexus RX 350 Lifestyle Photo

2021 Lexus RX 350 in Greenville, SC

Luxury is one of the finer things in life. For most people, it's typically something you dabble in occasionally. A fancy dinner here, a weekend getaway there. The question we have is: why only dabble? In the 2021 Lexus RX 350, you're going to have to get used to luxury every time you get into the driver's seat. Premium audio streaming? You have it. Top-of-the-line interior? Check. The most advanced safety technology to date? Of course. The list of amenities that go above and beyond for the modern driver is endless. Next time you're in your car, ask yourself if you deserve premium luxury on every drive you take. We think the answer will be a resounding yes.

If you're in the upstate, come test-drive your own 2021 RX 350 today!

2021 Lexus RX 350 Exterior Photo

Main Features


2021 Lexus RX 350 Interior
  • Heated front seats
  • Dual-zone automatic climate control
  • Eight-inch Lexus Multimedia System display


2021 Lexus RX 350 Technology Features
  • Apple CarPlay® & Android Auto™ integrations
  • Lexus Enform Wi-Fi
  • Voice Command


2021 Lexus RX 350 Safety Features
  • Pre-Collision System with Pedestrian Detection
  • Blind Spot Monitor with Rear Cross-Traffic Alert
  • Backup camera

Compare 2021 Lexus RX 350 Trims

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RX 350 Starting at $45,170*

2021 Lexus RX 350
  • 3.5L V6 engine
  • Eight-speed transmission
  • 18-inch alloy wheels
  • Rain-sensing windshield wipers
  • Dual-zone climate control
  • Leather-trimmed steering wheel
  • NuLuxe® interior trim
  • Lexus nine-speaker Premium Audio System
  • Eight-in Lexus Multimedia System with color LCD multimedia display
  • Voice Command
  • Amazon Alexa compatibility
  • Android Auto™ & Apple CarPlay®
  • Bluetooth® wireless technology
  • HD Radio™
  • Backup camera with dynamic gridlines
  • SmartAccess with push-button Start/Stop
  • Lexus Safety System+2.0
  • Pre-Collision System with Pedestrian Detection
  • Lane Tracing Assist
  • Lane Departure Alert with Steering Assist
  • Road Sign Assist
  • All-Speed Dynamic Radar Cruise Control
  • Intelligent High Beams
  • Blind Spot Monitor with Rear Cross-Traffic Alert
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RX 350L Starting at $48,000*

2021 Lexus RX 350L
  • Includes RX 350 features, plus:
  • Power-folding and reclining 50/50 split third-row seat
  • Second-row armrest storage compartment with two USB ports
  • Three-zone climate control
  • Aluminum roof rails
  • Concealed exhaust
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RX 350 F SPORT Starting at $48,650*

2021 Lexus RX 350 F SPORT
  • Includes RX 350 features, and adds or replaces:
  • F SPORT 20-inch split-10-spoke alloy wheels with Dark Graphite finish
  • F SPORT front seats with enhanced bolsters
  • F SPORT perforated leather—trimmed steering wheel and shift knob
  • Performance-inspired instrumentation
  • Scored Aluminum interior trim
  • Aluminum pedals and door-sill scuff plates
  • Black headliner
  • LED ambient interior illumination
  • F SPORT front fascia and mesh grille insert
  • F SPORT front-fender and rear-door badges
  • Black outside mirrors
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Upgrade to a 2021 Lexus RX 350 Today

Allow yourself more luxury in your life. We promise you'll enjoy it. The 2021 Lexus RX 350 is your ticket to a daily drive of luxury. Come test-drive yours today at Lexus of Greenville. We love helping our drivers in the upstate take the next step in their vehicle journey. If your current car needs serviced, we have you covered there, too. Our expert technicians can easily diagnose your issue and get you back on the road in an efficient manner. 

2021 Lexus RX 350 Lifestyle Photo

Frequently Asked Questions

Q: Does the 2021 RX 350 require premium gas?

A: Premium gas is recommended for the RX 350.

Q: Does the 2021 RX 350 have Apple CarPlay®?

A: Yes! Apple CarPlay® comes standard alongside Android Auto™ capability.

Q: How much is the 2021 Lexus RX 350?

A: The 2021 RX 350 ranges in price from $45,170* to $48,650* without any enhanced packages or add-ons.

Expert Opinions


“The original Lexus RX was a hugely influential vehicle, arriving in the late 1990s to help pioneer the luxury crossover SUV segment. It’s been the template for dozens of competitors since. The latest 2021 RX 350 does its predecessors proud. It’s quiet, comfortable and offers a lot of features for less money than much of the competition. There’s also a fuel-efficient RX 450h hybrid version and longer RX 350L that uses the extra space to fit a third row of seating (both of those are reviewed separately).”


“The 2021 Lexus RX 350 and hybrid RX 450h remain two of the most desirable luxury midsize SUV/crossovers. Not surprising, since the RX pretty much invented this vehicle class.”


“Most of (the RX’s) positives are hallmarks of other good Lexus vehicles: outstanding predicted reliability, great overall quality, and a long list of standard and optional infotainment features and active safety tech. With a robust V6 engine, the RX is no slouch off the line, and it corners with poise.”

*All prices are Manufacturer’s Suggested Retail Price (MSRP). MSRP excludes destination and handling charges, tax, title, license and options. Dealer sets actual price.

^Options listed are based on the RX 350L model.